腹腔镜术联合醋酸曲普瑞林治疗子宫内膜异位症的临床效果(1)
[摘要]目的 探讨腹腔镜术联合醋酸曲普瑞林治疗子宫内膜异位症(EMT)的临床效果。方法 选取2015年10月～2017年12月我院收治的90例EMT患者作为研究对象，用电脑随机分为两组，每组各45例。观察组实施腹腔镜术与醋酸曲普瑞林治疗；对照组采取腹腔镜术与孕三烯酮治疗，对两组临床指标、不良反应发生率和复发情况进行观察。结果 观察组排卵恢复时间(15.22±1.02)d，月经恢复时间(26.52±1.02)d，显著短于对照组排卵恢复时间(23.59±1.65)d，月经恢复时间(39.38±1.65)d，差异均有统计学意义(P<0.05)。观察组不良反应总发生率低于对照组(P<0.05)；观察组复发率低于对照组，差异均有统计学意义(P<0.05)。结论 腹腔镜术与醋酸曲普瑞林治疗EMT具有显著效果，同时能有效改善患者各项指标，安全性较高，值得推广。
[关键词]腹腔镜术；醋酸曲普瑞林；子宫内膜异位症
[中图分类号] R713 [文献标识码] A [文章编号] 1674-4721(2018)9(a)-0118-03
[Abstract] Objective To explore the clinical effect of laparoscopy combined with Triptorelin Acetate in the treatment of endometriosis (EMT). Methods A total of 90 patients with EMT treated in our hospital from October 2015 to December 2017 were selected as study subjects and randomly divided into two groups， 45 cases in each group. In the observation group， laparoscopic surgery combined with Triptorelin Acetate was adopted， while in the control group， laparoscopic surgery with Gestrinone was used. The clinical indicators， incidence of adverse reactions， and recurrence rate were compared in the two groups. Results The recovery time of ovulation and menstruation in the observation group were (15.22±1.02) d and (26.52±1.02) d， significantly shorter than those of the control group， (23.59±1.65) d and (39.38±1.65) d respectively (P<0.05). The total incidence of adverse reactions in the observation group was lower than that in the control group (P<0.05). The recurrence rate of patients with EMT in the observation group was lower than that in the control group， the differences were statistically significant (P<0.05). Conclusion Laparoscopy combined with Triptorelin Acetate obtains a significant effect on the treatment of EMT， and can effectively improve the patient′s various indicators in high safety simultaneously， which is worthy of study.
[Key words] Laparoscopy； Triptorelin Acetate； Endometriosis
子宮内膜异位症(EMT)为临床上十分常见的女性疾病，该病主要是指在子宫以外出现的子宫内膜组织，在临床上有极高的发病率，以育龄期妇女作为常见人群，尤以盆腔子宫内膜异位多见，易导致患者出现性交痛、不孕和慢性盆腔疼痛等，对患者的生活质量和身心健康造成严重影响[1]。目前临床上对盆腔EMT常采取手术治疗，但由于常规手术有远处转移、微小病灶肉眼不可见等特点，易导致患者复发率升高。近年来，随着我国腹腔镜技术的不断发展，腹腔镜联合药物治疗现已成为治疗盆腔EMT的常用方法，且疗效十分显著[2]。本研究对腹腔镜术联合醋酸曲普瑞林治疗EMT的临床效果进行分析，现报道如下。
1资料与方法
1.1一般资料
选取我院2015年10月～2017年12月收治的90例EMT患者，电脑随机分为两组，每组各45例。所有患者均同意本研究，并经我院医学伦理委员会批准。纳入标准：①患者均符合EMT的诊断标准，且确诊为EMT。②患者心肝肺肾等功能均属于正常状态。③均符合腹腔镜手术指征，无麻醉禁忌证。排除标准：①伴有肝肾功能障碍者。②伴有糖尿病和心脏病等基础性疾病。③伴有子宫手术史和子宫疾病者。④不同意本研究者。⑤伴有严重精神障碍和恶性肿瘤疾病者。观察组年龄25～47岁，平均(36.01±1.02)岁。对照组年龄24～47岁，平均(35.45±1.02)岁。两组的一般资料比较，差异无统计学意义(P>0.05)，具有可比性。, 百拇医药(杨小梅 卫凤英 杨玮林)
[关键词]腹腔镜术；醋酸曲普瑞林；子宫内膜异位症
[中图分类号] R713 [文献标识码] A [文章编号] 1674-4721(2018)9(a)-0118-03
[Abstract] Objective To explore the clinical effect of laparoscopy combined with Triptorelin Acetate in the treatment of endometriosis (EMT). Methods A total of 90 patients with EMT treated in our hospital from October 2015 to December 2017 were selected as study subjects and randomly divided into two groups， 45 cases in each group. In the observation group， laparoscopic surgery combined with Triptorelin Acetate was adopted， while in the control group， laparoscopic surgery with Gestrinone was used. The clinical indicators， incidence of adverse reactions， and recurrence rate were compared in the two groups. Results The recovery time of ovulation and menstruation in the observation group were (15.22±1.02) d and (26.52±1.02) d， significantly shorter than those of the control group， (23.59±1.65) d and (39.38±1.65) d respectively (P<0.05). The total incidence of adverse reactions in the observation group was lower than that in the control group (P<0.05). The recurrence rate of patients with EMT in the observation group was lower than that in the control group， the differences were statistically significant (P<0.05). Conclusion Laparoscopy combined with Triptorelin Acetate obtains a significant effect on the treatment of EMT， and can effectively improve the patient′s various indicators in high safety simultaneously， which is worthy of study.
[Key words] Laparoscopy； Triptorelin Acetate； Endometriosis
子宮内膜异位症(EMT)为临床上十分常见的女性疾病，该病主要是指在子宫以外出现的子宫内膜组织，在临床上有极高的发病率，以育龄期妇女作为常见人群，尤以盆腔子宫内膜异位多见，易导致患者出现性交痛、不孕和慢性盆腔疼痛等，对患者的生活质量和身心健康造成严重影响[1]。目前临床上对盆腔EMT常采取手术治疗，但由于常规手术有远处转移、微小病灶肉眼不可见等特点，易导致患者复发率升高。近年来，随着我国腹腔镜技术的不断发展，腹腔镜联合药物治疗现已成为治疗盆腔EMT的常用方法，且疗效十分显著[2]。本研究对腹腔镜术联合醋酸曲普瑞林治疗EMT的临床效果进行分析，现报道如下。
1资料与方法
1.1一般资料
选取我院2015年10月～2017年12月收治的90例EMT患者，电脑随机分为两组，每组各45例。所有患者均同意本研究，并经我院医学伦理委员会批准。纳入标准：①患者均符合EMT的诊断标准，且确诊为EMT。②患者心肝肺肾等功能均属于正常状态。③均符合腹腔镜手术指征，无麻醉禁忌证。排除标准：①伴有肝肾功能障碍者。②伴有糖尿病和心脏病等基础性疾病。③伴有子宫手术史和子宫疾病者。④不同意本研究者。⑤伴有严重精神障碍和恶性肿瘤疾病者。观察组年龄25～47岁，平均(36.01±1.02)岁。对照组年龄24～47岁，平均(35.45±1.02)岁。两组的一般资料比较，差异无统计学意义(P>0.05)，具有可比性。, 百拇医药(杨小梅 卫凤英 杨玮林)