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表现为胃肠道症状的脊柱结核患者临床特点的回顾性分析(1)
http://www.100md.com 2018年5月1日 《新医学》 20185
     【摘要】目的探討表现为胃肠道症状(GIS)的脊柱结核患者的发病部位及临床表现。方法选取住院就诊的脊柱结核患者。根据是否表现为GIS,将患者分为GIS组和非GIS(NGIS)组。比较2组患者脊柱感染节段分布和并发症发生率。结果共纳入36例GIS组患者和162例NGIS组患者。GIS组患者脊柱病变椎体节段主要在胸7~11,占病变椎体节段总数的598%(64/107),而NGIS组患者病变椎体节段主要在胸12~腰5,占总数的573%(231/403),2组脊柱病变节段分布差异有统计学意义(P<0001)。GIS组和NGIS组分别有10例(278%)和13例(80%)患者出现神经根压迫,组间比较差异有统计学意义(P=0001);GIS组有23例患者(639%)出现椎旁、腰大肌冷脓肿,高于NGIS组(469%,P=0032)。椎管内脓肿发生率在2组间比较差异无统计学意义(83% vs 37%, P=0445)。结论表现为GIS的脊柱结核患者,其脊柱病变节段主要位于低位胸段,且有更高的脊柱神经根压迫、椎旁和腰大肌冷脓肿并发症发生率。

, 百拇医药     【关键词】脊柱结核;胃肠道症状;病变椎体;并发症

    Retrospective analysis of clinical characteristics of spinal tuberculosis patients presenting with gastrointestinal symptomsWu Tingfeng, Li Jieyao, Wang Siyi, Xu Jihao, Chen Qikui, Yu Tao Department of Gastroenterology, Sun YatSen Memorial Hospital, Sun Yatsen University, Guangzhou 510120, China

    Corresponding author, Li Jieyao, Email: 173745022@qqcom

    【Abstract】ObjectiveTo investigate the onset site and clinical symptoms of spinal tuberculosis patients presenting with gastrointestinal symptom(GIS) MethodsPatients with spinal tuberculosis who were hospitalized at Sun Yatsen Memorial Hospital of Sun Yatsen University from January 2003 to December 2016 were selected Based upon the incidence of GIS, all patients were divided into the GIS and nonGIS (NGIS) groups The distribution of infected spinal segments and the incidence of complications were statistically compared between two groups ResultsIn this study, 36 patients were assigned into the GIS group and 162 into the NGIS group In the GIS group, the affected spinal segments were predominantly located from thoracic (T) 7 to 11, accounting for 598% (64/107), and 573% (231/403) from T12 to lumber (L) 5 in the NGIS group The distribution of the infected segments significantly differed between two groups (P<0001) In the GIS group, the incidence rate of spinal cord compression was 278% (10/36), significantly higher compared with 80% (13/162) in the NGIS group (P=0001) In the GIS group, 639% patients (23/36) presented with paravertebral or psoas abscess, considerably higher than 469% (76/162) in the NGIS group (P=0032) The incidence of intraspinal abscess did not significantly differ between the GIS and NGIS groups (83% vs 37%, P=0445) ConclusionsFor spinal tuberculosis patients presenting with GIS, the lower thoracic segments are primarily affected Moreover, the incidence of spinal cord compression, paravertebral and psoas abscess is significantly higher compared with their counterparts without GIS, 百拇医药(吴挺丰 黎洁瑶 王思仪 许稷豪 陈其奎 于涛)
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